Rab25 in head and neck cancer metastasis 1 Rab25 regulates invasion and metastasis in head and neck cancer
نویسندگان
چکیده
Panomwat Amornphimoltham, Kamil Rechache, Jamie Thompson, Andrius Masedunskas, Kantima Leelahavanichkul, Vyomesh Patel, Alfredo Molinolo, J. Silvio Gutkind, and Roberto Weigert* Intracellular Membrane Trafficking Unit and 2 Molecular Carcinogenesis Unit Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research, National Institutes of Health 30 Convent Dr. Building 30 Room 303A, Bethesda, MD 20892-4340
منابع مشابه
Rab25 regulates invasion and metastasis in head and neck cancer.
PURPOSE Head and neck squamous cell carcinoma (HNSCC) is one of the 10 most common cancers with a 50% five-year survival rate, which has remained unchanged for the past three decades. One of the major reasons for the aggressiveness of this cancer is that HNSCCs readily metastasize to cervical lymph nodes that are abundant in the head and neck region. Hence, discovering new molecules controlling...
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Purpose:Head andneck squamous cell carcinoma (HNSCC) is one of the 10most common cancers with a 50% five-year survival rate, which has remained unchanged for the past three decades. One of the major reasons for the aggressiveness of this cancer is that HNSCCs readilymetastasize to cervical lymph nodes that are abundant in the head and neck region. Hence, discovering new molecules controlling th...
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Currently there are no molecular markers able to predict clinical outcome in locally advanced head and neck squamous cell carcinoma (HNSCC). In a previous microarray study, RAB25 was identified as a potential prognostic marker. The aim of this study was to analyze the association between RAB25 expression and clinical outcome in patients with locally advanced HNSCC treated with standard therapy....
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